Tablet Presentation

Each Tablet Contains:
Sitagliptin IP 25 mg/50 mg/100 mg

Sitagliptin tablet contains the active substance sitagliptin which is a member of a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors) that lowers blood sugar levels in adult patients with type 2 diabetes mellitus.
This medicine helps to increase the levels of insulin produced after a meal and decreases the amount of sugar made by the body.

What is type 2 diabetes?

Type 2 diabetes is a condition in which your body does not make enough insulin, and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar. When this happens, sugar (glucose) builds up in the blood.

Indication

It is a prescription medicine used along with diet and exercise to lower blood sugar in adult patients with type 2 diabetes
Note: Sitagliptin is not used to treat type 1 diabetes (a condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood).

Mechanism of action

Sitagliptin is a member of the gliptin class of anti-diabetic medications. Its mechanism of action is through inhibition of dipeptidyl peptidase-4 (DPP-4), an enzyme that acts to degrade and inactivate glucagon-like peptide-1 (GLP-1). Sitagliptin works by increasing the amount of insulin that your body makes. Insulin is the hormone that controls sugar levels in your blood.

Side Effects

• Headache
• Upper respiratory infection
• Stuffy or runny nose and sore throat

Contraindication

• Sitagliptin is contraindicated in patients with previous hypersensitivity to Sitagliptin or any other component of this drug
• If any have kidney problems, heart diseases
• Type 1 disease

Drug Interaction

Tell your doctor if you are taking digoxin (a medicine used to treat irregular heartbeat and other heart problems).

Warning & Precaution

• During Pregnancy and Breastfeeding please consult your doctor before taking any medicine
• This medicine has no or negligible influence on the ability to drive and use machines

Dosage

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitagliptin Tablet may be taken with or without food, but it is better to take it at a fixed time.
You should keep taking this medicine for as long as your doctor recommends.

Storage

Store in a cool, dry & dark place. Protected from direct sunlight.

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